We also confirmed mTORC1-TFEB pathway alterations in an additional PD iPSC line harboring the GBA1-E326K mutation, which has been recently identified as the most prevalent PD-associated GBA1 mutation and is known to be absent in the GD population (Duran et al., 2013; Avenali et al., 2020). Here, TFEB is linked to Parkinson disease.