HLA-DRB1 and systemic lupus erythematosus: Wunnenburger et al. reported that SLE risk variant (TNXB) is associated with CKD attributed to type 1 diabetes mellitus (p < 0.01), and IgA nephropathy (HLA-DRB1) was related to granulomatosis with polyangiitis (p < 0.01) (27).