IGHE and allergic asthma: In the retrospective REALITY study (131 patients with IgE 30–700 IU/mL and 67 with IgE >700 IU/mL), ∼70% of patients with moderate-to-severe allergic asthma with a mean IgE level of 1046 IU/mL (range, 23–10,979 IU/mL) had a complete response to omalizumab.