mTOR is present as two multiprotein complexes, mTORC1 (mechanistic target of rapamycin complex 1) and m,TORC2, and is regulated by the PI3K/Akt signaling pathway, which integrates growth factor signaling with tumor cell metabolism, as well as the LKB1/AMPK (liver Kinase B1/5′AMP-activated protein kinase) pathway, controlling the energy status of the cell [25, 26]. Here, STK11 is linked to neoplasm.