Analyses of specific sarcoma subtypes from the TCGA dataset showed that some of them did not show ERK5 molecular alterations (synovial sarcoma (n = 10) and desmoid fibromatosis (n = 2)), while others presented high alteration frequencies (dedifferentiated liposarcoma (20.69%, n = 58)); malignant peripheral nerve sheath tumor (33.33%, n = 9); leiomyosarcoma (45.92%, n = 98); myxofibrosarcoma (45.83%, n = 24) (Fig. 2c). Here, MAPK7 is linked to malignant peripheral nerve sheath tumor.