Findings also indicate the expression of a large amount of cytokine by SARS-CoV-2 infected CD4+ T-cells, which is markedly associated with viral persistence and disease severity.[7] Furthermore, it is known that pre-existing underlying diseases, commonly observed due to increased survival in PLHIV, are considered potential risk factors for the severity of COVID-19 in this population.[8]. The gene discussed is CD4; the disease is COVID-19.