The enrichment analysis indicated that upregulated DEGs in cluster A were mainly enriched in cellular metabolism pathways (such as retinol metabolism, drug metabolism by cytochrome P450, and xenobiotics metabolism by cytochrome P450), and tumor-related signaling pathways (such as Wnt/β catenin pathways, DNA repair, p53 pathways, and unfolded protein response). This evidence concerns the gene TP53 and neoplasm.