Negative binomial regression with propensity score-based IPTW showed that the use of SC insulin was associated with higher counts of hyperglycaemia (> 1.8 g/L) (IRR: 3.45 [95%CI 2.97; 4.00]; P < 0.0001) (Additional file 1: Table S8). The gene discussed is INS; the disease is Hyperglycemia.