To further explore the relationship between PRDX6 and COPD, Sundar et al. demonstrated through in vivo animal experiments that after a short period of exposure to cigarette smoke, PRDX6 knockout mice would not accumulate inflammatory cells in large numbers, and the levels of pro‐inflammatory factors in the lungs did not change compared with those in the wild mice.21 Here, PRDX6 is linked to chronic obstructive pulmonary disease.