The rs1800629 of TNFA was also significantly associated with the susceptibility to lymphoma in the dominant, overdominant, codominant, additive and allelic models, and the risk of patients with genotype A was lower than that with genotype G (all p < 0.05), indicating the protective role for genotype A. For IL4, the rs2070874 and rs2243250 were correlated with the risk of lymphoma in the dominant, overdominant and codominant models, and the patients with CT genotype were significantly lower than those with the TT genotype. Here, IL4 is linked to lymphoma.