ACE2 and COVID-19: This comprehensive study evaluated the several SNPs located on ACE1 rs1799752 (I/D) and ACE2 (rs1978124, rs2285666, and rs2074192) genes in a cohort of 4330 Iranian patients positive for different SARS-COV-2 variants, divided into 2307 recovered and 2023 deceased COVID-19 patients.