Colocalization analysis supported a shared causal variant between ADRD and PD at the CLU (88.4% chance), WWOX (80.4% chance), and LCORL (65.3% chance) loci; between ADRD and ALS at the TSPOAP1 locus (73.9% chance); and between PD and ALS at the NEK1 (98.9% chance) and GAK/TMEM175 (98.3% chance) loci. Here, TMEM175 is linked to Parkinson disease.