There were statistically significant differences between the four groups regarding sex, age, BMI, smoking status, diabetes, CKD, ischemic stroke history, dyslipidemia and statin use, and HDL-C, UA, P, TG, FFA, Cr, cystatin C, HbA1C, TNT, and apoA levels (P < 0.05). This evidence concerns the gene CST3 and ischemic stroke.