The SNP rs4420638 (NM_001645.3, c.*459A > G) located approximately 340 bp from the 3’ end of the apolipoprotein C-I (APOC1) gene, in the chromosomal region 19q13.32, tags a linkage disequilibrium (LD) block involving the TOMM40, APOE, and APOC1 genes (Suchindran et al. 2010; Beekman et al. 2013), and has been implicated in dyslipidemia by numerous genetic association studies [GWAS Catalog EMBL-EBI (http://www.ebi.ac.uk/gwas; accessed on January 24, 2023)] (Sollis et al. 2023). This evidence concerns the gene APOC1 and metabolic syndrome.