Further, the youngest age of our participants (mean age of our participants 53.7 ± 17.2 vs 75.2 ± 10.9), the highest mean RVSP (mean RVSP: 60.6 ± 16.7 vs 44.9 ± 13.1 mmHg), and a significant proportion of people living with HIV infection (20% of participants with valid test) and with a lower CD4 count (latest vs nadir mean (SD) CD4 count: 336.2 (204.1) vs 253.3 (212.9) cells per 106/L) may restrict the generalizability of our findings, but it is also a call to action to adequately document PH-LHD in Africa. Here, CD4 is linked to HIV infectious disease.