In the ssGSEA algorithm, CXCL10 had a significant correlation with activated CD8 T cell, activated B cell, MDSC, activated CD4 T cell, and immature B cell and a significant inverse correlation with CD56dim natural killer cell, central memory CD4 T cell, plasmacytoid dendritic cell, immature dendritic cell, neutrophil, mast cell, monocytein, etc. in the RA training set (Fig. 9E). The gene discussed is CD4; the disease is rheumatoid arthritis.