Compared to the control group, ELJNV + Laser increased the tumor-infiltrating CD8+ T cells and IFN-γ+CD8+ T cells by 8.9- and 11.1-fold and decreased Tregs by 5.6-fold, respectively (Fig. 7i, j and Supplementary Fig. 49a–f). The gene discussed is IFNG; the disease is neoplasm.