On the other hand, we did not see significant increases in HBeAg over time in the supernatants after infection, even though we detected HBV RNA- and HBc-positive cells by ISH, IHC and IF, as well as significant HBsAg levels in the supernatant for HBV and HBV/WMHBV preS1[1–48] virus infection of HepG2 cells expressing marmoset NTCP. This evidence concerns the gene KRT88P and infection.