As a recent hot topic of epigenetic area, studies on the biological functions of mRNA ac4C modification have sprung up.[27, 28, 29, 30, 31, 32, 33, 34, 35] Consistent with previous studies,[35] we also observed that acetyltransferase NAT10 expression was upregulated in GC and positively correlated with a poor prognosis in GC patients. Here, NAT10 is linked to gastric cancer.