PALM2AKAP2 and esophageal cancer: According to the proteomic data, it can be concluded that the expression of PALM2 is up-regulated in esophageal cancer (Fig. 2A), and high expression was associated with shorter survival time of patients with esophageal cancer (Fig. 2B), which was not affected by the age, sex, smoking, drinking, and other factors of patients with esophageal cancer, and was an independent prognostic factor for esophageal cancer patients (Fig. 2C).