Flow cytometric analysis of tumor immune infiltrates in Cd1d1-restored tumors indicates more abundant Cd1d-restricted NKT cells (P=0.0042), along with increased binding to the high affinity synthetic NKT cell ligand alpha-Galactosyl Ceramide (α-GalCer) tetramer and an increase in the CD69 marker of NKT cell activation (P=0.0099) (Figures 5E and S9A–C). Here, CD1D is linked to neoplasm.