TNFRSF1B and skin infection: The efficacy of the TNFR2 agonist against the P. aeruginosa skin infection was not due to direct antibacterial activity, as there were no differences in the growth curves of P. aeruginosa incubated with varying concentrations of the TNFR2 agonist (80, 160, and 320 μg/ml) and vehicle control (fig.