SOD1 and Down syndrome: Notably, his research focuses on neural cell-related death mechanism.[13,14] Halliwell B, who published “Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defenses: relevance to Down’s syndrome and familial amyotrophic lateral sclerosis,”[15] had the highest number of citations.