Apocynin can inhibit NADPH oxidase activation and increase superoxide dismutase by decreasing the level of total protein and TNF-α; thus, it has a significant protective effect on lipopolysaccharide-induced acute respiratory distress syndrome in mouse models [41], suggesting that the mycelia of O. sinensis mitigates the inflammatory response and oxidative stress by regulating the levels of apocynin and other substances, which, in turn, have a protective effect on the lungs. The gene discussed is FMO5; the disease is acute respiratory distress syndrome.