Most notably, H19 rs217727 polymorphism has been associated with susceptibility to type 2 diabetes in Iranian population (Ghaedi et al. 2018) and ischemic stroke in Chinese population (Zhu et al. 2018).rs2839698 is another SNP within H19 whose association with cancer susceptibility has been assessed in recent years (Yu et al. 2020; Safari et al. 2019). Here, H19 is linked to ischemic stroke.