DHX9 and systemic lupus erythematosus: In this study, we report that DHX9, as an autoantigen in the sera of systemic lupus erythematosus patients, is highly expressed in the PBMCs from patients with CAD, and interacts with p65 in macrophages to enhance the transcriptional activity of DHX9-p65-RNA Polymerase II complex to produce inflammatory factors (Fig. 7).