Soluble D‐dimer, produced as a result of fibrin network degradation from fibrin‐bound plasmin, is a pivotal biomarker of hypercoagulability and thrombosis associated with clinical indications, such as tumor stage, metastasis, and growth, in a large number of cancers, and used to predict survival independent of clinical stage, histologic tumor type, and performance status in lung cancer patients.23, 24. Here, PLG is linked to neoplasm.