By utilizing TIMER dataset, it was observed that BIRC5 expression was positively correlated with MDSC infiltration score in multiple cancers (Figure 5A,B), and survival analysis demonstrated that patients with higher BIRC5 expression and MDSC infiltration score had shorter OS time in sarcoma, lung adenocarcinoma, kidney renal clear cell carcinoma, and adrenocortical carcinoma (Figure 5C). This evidence concerns the gene BIRC5 and lung adenocarcinoma.