NLRP3 and graft versus host disease: In study by Chen et al., miR-155–deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation, supported by the fact that Nlrp3/miR-155 double-knockout allo-HSCT recipient mice had no increased protection from GVHD compared with Nlrp3−/− recipients (110).