SNPs in inflammasome-associated genes including NLRP1 (rs8079034C and rs878329C) (141), NLRP3 (rs3806265, rs10754557 and rs10733113) (142, 143), AIM2 (rs2276405) (144), and CARD8 (rs2043211) (142) have been associated with increased susceptibility to psoriasis in affected patients compared to healthy controls in a number of studies in different ethnic subgroups. The gene discussed is NLRP3; the disease is psoriasis.