7 HLA alleles including HLA-B*59:01:01, HLA-C*15:02:01, HLA-DRB1*04:05:01, HLA-DQB1*04:01:01, HLA-DQB1*06:01:01, HLA-DQA1*01:03:01 and HLA-DQA1*03:03:01 were significantly associated with susceptibility to PBC-AIH after adjusting for multiple corrections. This evidence concerns the gene HLA-B and primary biliary cholangitis.