GATA1 and Dravet syndrome: ML-DS is driven by overexpressed genes and micro-RNAs located on chromosome 21, GATA1 (GATA Binding Protein 1) mutations, and a range of other somatic mutations, in particular those affecting cohesin molecules, signaling pathways, epigenetic regulators, and hematopoietic transcription factors (Boucher et al., 2021; de Castro et al., 2021; Grimm et al., 2021).