CBFA2T3 participates in hemopoietic stem cell (HSC) self-renewal and differentiation, megakaryocyte-erythrocyte progenitor development, and leukemia stem cell (LSC) expansion (Steinauer et al., 2017; Masetti et al., 2019a; Steinauer et al., 2019; Steinauer et al., 2020; Jakobczyk et al., 2021). This evidence concerns the gene CBFA2T3 and leukemia.