ENTPD1 and preeclampsia: In the human placenta, both CD39 and CD73 have been detected in the villous trophoblast compartment at term (Thomson et al., 1990; Jaakkola et al., 2000; Kittel et al., 2004; Zhu et al., 2018), and their role in the pathogenesis of preeclampsia seems currently rather controversial.