To identify these targets, we overlaid the small intestine and colon MALAT1-dependent transcripts identified from the DESeq and rMATS analysis and found 30 targets that were dependent on MALAT1 at the overall RNA expression or alternative splicing levels (Figure 6A), including those encoding an acetylglucosaminyltransferase MGAT4C, an aldehyde dehydrogenase ALDH1A1, and an adenylate kinase AK4 that have been previously implicated in other types of cancers. This evidence concerns the gene AK4 and cancer.