A total of six studies were included in the analysis of basal FSH levels (Oktay et al., 2006; Lutchman Singh et al., 2007; Quintero et al., 2010; Das et al., 2011; Gunnala et al., 2019; Porcu et al., 2020) (Supplementary Table S3), and the weighted mean basal FSH values were not statistically significant between the cancer patients and control groups (WMD = 0.00, 95% CI = −0.85 to 0.85, P = 0.997) (Fig. 3). Here, BRD2 is linked to cancer.