Previous studies have shown that multiple viruses including Herpes simplex virus, Porcine circovirus, Influenza A viruses, vaccinia and cowpox viruses utilize the PI3K/Akt signalling pathways for replication and establising successful infection (Ehrhardt et al., 2007; Soares et al., 2009; Wei et al., 2012; Eaton et al., 2014). The gene discussed is AKT1; the disease is infection.