TGFB1 and diabetic kidney disease: The heatmap shown in Figure 3A emphasized that genes involved in the pathology of DKD, including TGF-β, ECM, fibrosis, oxidative stress, mitochondria, inflammation, and ER stress pathways, are upregulated by TGF-β in WT MMC but attenuated in lncMGC-KO5 MMC, suggesting that lncMGC has widespread effects on gene expression regulated by TGF-β (Figure 3A).