KRAS and cancer: However, there were no significant correlations between family history of cancer and TEs for patients based on 1:1 KRAS mutations matching analysis, while family history of cancer was significantly negatively correlated with Fe (r = -0.26, p < 0.05), Se (r = -0.25, p < 0.05), and Zn (r = -0.22, p < 0.05) for patients with 1:1 MSI matching, indicating the occurrence of different molecular events was associated with different alterations in types and levels of TEs (Fig. 3 and 5).