ARG1 and neoplasm: For the macrophage subsets, treatment with CpG-2722 alone and combination of CpG-2722 and BPRDP056 promoted F4/80+ macrophage and iNOS+ M1 macrophage accumulation in tumors; conversely, no treatment affected the level of ARG-1 M2 macrophages in the tumor (Figure S1B).