HEBP1 and diabetes mellitus: Our recent genome-wide transcriptome analyses and animal studies demonstrate that Hebp1 derived from MCPs can rescue cavernous endothelial cell and neuronal cell contents and modulate ROS levels and PI3K/AKT/eNOS signaling activity in a mouse model of diabetes-induced ED.5, 25 In the absence of reports on Hebp1 in peripheral nerve injury, we hypothesized that Hebp1 plays a beneficial role in CNI-induced ED.