IL22 and myocardial ischemia: CircPTK2 could serve as a sponge of miR-1278 221, miR-139-3p 222, and miR-758-3p (miR-758) 223, MiR-1278 suppressed cardiomyocyte inflammation in myocardial ischemia by reducing IL-22 and CXCL14 expression 224, suggesting that circPTK2 promotes cholesterol synthesis and inflammation by regulating the miR-892b/DHCR24 axis and miR-1278/IL-22 and CXCL14 axis.