PBX1 and cancer: PBX1 (Pre-B cell leukemia transcription factor 1) is a member of the TALE (three amino acid loop extension) class of homeodomain transcription factors, which is related to the occurrence and development of many cancers, including those derived from stomach4, ovary5, blood6, and prostate cells7, however, the role of PBX1 in NSCLC is not well known.