Moreover, in patients undergoing angioplasty, nano‐curcumin at the same dose caused a significant decrease in hs‐CRP levels (Helli et al., 2021).Besides, the systematic review had shown that curcumin improved the severity of inflammation including asthma, inflammatory bowel disease, and juvenile idiopathic arthritis (Heidari et al., 2022). The gene discussed is MAP3K14; the disease is inflammatory bowel disease.