IL6 and major depressive disorder: These findings are partly consistent with previous meta-analyses on the weakened emotional responses of the dorsal and lateral amygdala in PTSD (25) and MDD (23), as well as with previous findings on a flattened IL-6 diurnal pattern in individuals who underwent childhood trauma or combat-zone deployment (54, 55), which confer a risk of developing stress-related mental disorders (90, 91).