This notion is supported by fact that individuals with lower serum vitamin C are at higher risk of severe COVID-19 (104), whereas intravenous administration of vitamin C in critically ill COVID-19 patients improved the symptomatology, lowered IL-6 circulating levels (107) potentially countering the cytokine storm, decreased mortality (104) and shortened the stay in the intensive care unit (108). This evidence concerns the gene IL6 and COVID-19.