NFKB1 and colitis: Zhu et al. (2020b) further found that baicalin probably protected mice against UC via maintaining Th17/Treg balance and modulating both gut microflora and SCFAs. Among the research from Zhang et al. (2017), they proved that baicalin could attenuate DSS-evoked UC via restraining IL-33 expression and NF-κB excitation. Shen et al. (2019) also discovered that baicalin exerted a regulatory role on the IKK/IKB/NF-κB signal cascade and apoptosis-associated proteins in murine models of colitis.