In addition, the N-acetylgalactosamine transferase 2-angiopoietin like protein 3-lipoprotein lipase (GALNT2-ANGPTL3-LPL) pathway, which is closely related to dyslipidemia and able to directly affect HDL metabolism, has been reported to be effectively regulated by paeoniflorin (Khetarpal et al., 2016; Xiao et al., 2017). This evidence concerns the gene LPL and metabolic syndrome.