For example, in the section on diabetic nephropathy, further clarifications on GluT4 and AMPK signaling and EFK-related mechanisms in recent years can be introduced for hypoglycemic effects; for antioxidant effects, the interaction between the peroxisome pathway and Nrf2 and other important antioxidant pathways in diabetic nephropathy (DN) and quercetin can be introduced; for autophagy promotion, the changes in autophagy-related LC3 and the expression of other related proteins can be systematically discussed. This evidence concerns the gene SLC2A4 and liver dysplastic nodule.