In summary, FA has protective and antioxidant effects on TAA-induced hepatic fibrosis in rats by inhibiting the TGF-β1/Smad3 signalling pathway and differentially regulating the expression of microRNAs (miR-200, miR-30 and miR-21) in the liver(Hussein et al., 2020). The gene discussed is SMAD3; the disease is Hepatic fibrosis.