Other drugs that have shown promise in treating cholestatic liver diseases include pravastatin and fexofenadine (Hayashi and Sugiyama, 2009; Gonzales et al., 2012; Naoi et al., 2014; Gonzales et al., 2015), which have been reported to improve bile excretion and reduce serum bile acid levels in patients with BSEP deficiency. The gene discussed is ABCB11; the disease is Cholestatic liver disease.